Controlling Oncolytic Virus Growth & Gene Expression With Small Molecules
Time: 10:00 am
day: Day One
Details:
- Vaccinia virus has simple promoter structures and is amenable to modulation with transgenic genetic control elements
- Synthetic virology strategies can be used to design externally regulated virus promoters
- In mouse models, virus replication and/or transgene expression can be modulated using FDA approved small molecules
