Pre-Clinical PK, BD, & Immunogenicity Studies to Support FIM Studies with Vesicular Stomatitis Virus – Glycoprotein (VSV-GP)

Time: 10:30 am
day: Pre-Conference Day


  • Strategies and approaches employed to bring Vesicular Stomatitis Virus pseudotyped with LCMV glycoprotein (VSV-GP) through IND-enabling tox/biodistribution studies to enable first-in-man trials
  • More specifically, novel molecular toolset to capture time course of viral replication, understand the unique PK, analyze shedding, vector persistence, assess the time course kinetics of immune responses after both intravenous and intratumoral administration in mice